Self-reported sexual health: Breast cancer survivors compared to women from the general population – an observational study

作者：Anne Oberguggenberger, Caroline Lopes Martini, Nathalie Huber, Lesley J. Fallowfield, Michael Hubalek, Martin Daniaux, Barbara Sperner‐Unterweger, Bernhard Holzner, Monika Judith Sztankay, Eva‐Maria Gamper, Verena Meraner · 发表于：BMC Cancer · 年份：2017 · DOI：10.1186/s12885-017-3580-2 · 被引用次数：92 · 研究领域：Cancer survivorship and care、Sexual function and dysfunction studies、Menopause: Health Impacts and Treatments

BACKGROUND: Cancer survivorship is of increasing importance in post-treatment care. Sexual health (SH) and femininity can be crucial issues for women surviving cancer. We aimed to determine a more complete understanding of the contribution that a breast cancer (BC) diagnosis and its treatment exert on patients' follow-up SH. For this purpose, self-reported levels and predictors of SH in breast cancer survivors (BCS) were compared with those of women with no previous or current BC (WNBC). METHODS: BCS and WNBC underwent a comprehensive, cross-sectional patient-reported outcome (PRO) assessment. Validated PRO instruments were used to measure SH, body image, anxiety and depression and menopausal symptoms. Assessments were performed within the routine clinical setting. Instruments used were the Sexual Interest and Desire Inventory - Female, Sexual Activity Questionnaire, Body Image Scale, Hospital Anxiety and Depression Scale and the Menopause-Specific Quality of Life Questionnaire. RESULTS: One hundred five BCS (average time since diagnosis of 3 years) and 97 WNBC with a mean age of 49 years completed the assessment. SH was significantly worse in BCS compared to WNBC (p = 0.005; BCS SIDI-F mean = 24.9 vs. WNBC mean = 29.8). 68.8% of BCS and 58.8% of WNBC met criteria of a hypo-active sexual desire disorder. Higher depressive symptoms, higher age and lower partnership satisfaction were predictive for poorer SH in BCS. CONCLUSION: SH problems are apparent in BCS and differ signifi...