Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists

作者：Yingnan Zhang, Mark Ultsch, Nicholas J. Skelton, Daniel J. Burdick, Maureen H. Beresini, Wei Li, Monica Kong-Beltran, Andrew S. Peterson, John G. Quinn, Cecilia Chiu, Yan Wu, Steven Shia, Paul Moran, Paola Di Lello, Charles Eigenbrot, Daniel Kirchhofer · 发表于：Nature Structural & Molecular Biology · 年份：2017 · DOI：10.1038/nsmb.3453 · 被引用次数：67 · 研究领域：Monoclonal and Polyclonal Antibodies Research、Lipoproteins and Cardiovascular Health、RNA and protein synthesis mechanisms