Evaluation of the hemodynamics and right ventricular function in pulmonary hypertension by echocardiography compared with right-sided heart catheterization

作者：Yidan Li, Yidan Wang, Hong Li, Weiwei Zhu, Xiangli Meng, Xiuzhang Lu · 发表于：Experimental and Therapeutic Medicine · 年份：2017 · DOI：10.3892/etm.2017.4953 · 被引用次数：12 · 研究领域：Pulmonary Hypertension Research and Treatments、Cardiovascular Function and Risk Factors、Congenital Heart Disease Studies

The present study aimed to evaluate hemodynamics and right ventricular function in patients with pulmonary hypertension (PH) using transthoracic echocardiography and to compare these results with measurements obtained using right‑sided heart catheterization (RHC). A total of 75 patients with PH were examined using echocardiography and RHC. Patients were divided into the following two groups according to their difference between SPAPecho and SPAPRHC measurement: The overestimated group and underestimated group. The overestimated group included the subgroups groupover‑A (difference <20 mmHg) and groupover‑B (difference ≥20 mmHg), and the underestimated group included groupunder‑A (absolute value of the difference <20 mmHg) and groupunder‑B (absolute value of the difference ≥20 mmHg). SPAPecho measurements were revealed to be significantly positively correlated with SPAPRHC measurements (r=0.794; P<0.01). Among all echocardiographic measurements, only tricuspid annular plane systolic excursion (TAPSE) was significantly different between groups; it was increased in groupover‑A and groupunder‑A compared with groupover‑B (P<0.01). Although SPAP measurements obtained using echocardiography were significantly positively correlated with those obtained using RHC, a high proportion of overestimation or underestimation of SPAP by echocardiography remained.