The UCSC Genome Browser Database: 2008 update

作者：Donna Karolchik, Robert M. Kuhn, Robert Baertsch, G. P. Barber, Hiram Clawson, Mark E. Diekhans, Belinda M. Giardine, Rachel Harte, Angie S. Hinrichs, F. Hsu, Kord M. Kober, Webb Miller, Jakob Skou Pedersen, A. Pohl, Brian J. Raney, Brooke Rhead, Kate R. Rosenbloom, Kayla E. Smith, Mario Stanke, A. Thakkapallayil, Heather Trumbower, Ting Wang, Ann S. Zweig, David H. Haussler, W. James Kent · 发表于：Nucleic Acids Research · 年份：2007 · DOI：10.1093/nar/gkm966 · 被引用次数：527 · 研究领域：Genomics and Phylogenetic Studies、Gene expression and cancer classification、Bioinformatics and Genomic Networks

The University of California, Santa Cruz, Genome Browser Database (GBD) provides integrated sequence and annotation data for a large collection of vertebrate and model organism genomes. Seventeen new assemblies have been added to the database in the past year, for a total coverage of 19 vertebrate and 21 invertebrate species as of September 2007. For each assembly, the GBD contains a collection of annotation data aligned to the genomic sequence. Highlights of this year's additions include a 28-species human-based vertebrate conservation annotation, an enhanced UCSC Genes set, and more human variation, MGC, and ENCODE data. The database is optimized for fast interactive performance with a set of web-based tools that may be used to view, manipulate, filter and download the annotation data. New toolset features include the Genome Graphs tool for displaying genome-wide data sets, session saving and sharing, better custom track management, expanded Genome Browser configuration options and a Genome Browser wiki site. The downloadable GBD data, the companion Genome Browser toolset and links to documentation and related information can be found at: http://genome.ucsc.edu/.