Improper wound treatment and delay of rabies post-exposure prophylaxis of animal bite victims in China: Prevalence and determinants

作者：Qiaoyan Liu, Xiaojun Wang, Bing Liu, Yanhong Gong, Naomie Mkandawire, Wenzhen Li, Wenning Fu, Liqing Li, Yong Gan, Jun Shi, Bin Shi, Junan Liu, Shiyi Cao, Zuxun Lu · 发表于：PLoS neglected tropical diseases · 年份：2017 · DOI：10.1371/journal.pntd.0005663 · 被引用次数：62 · 研究领域：Rabies epidemiology and control、Injury Epidemiology and Prevention、Infection Control in Healthcare

BACKGROUND: Rabies is invariably a fatal disease. Appropriate wound treatment and prompt rabies post-exposure prophylaxis (PEP) are of great importance to rabies prevention. The objective of this study was to investigate the prevalence and influencing factors of improper wound treatment and delay of rabies PEP after an animal bite in Wuhan, China. METHODOLOGY: This cross-sectional study was conducted among animal bite victims visiting rabies prevention clinics (RPCs). We selected respondents by a multistage sampling technique. A face-to-face interview was conducted to investigate whether the wound was treated properly and the time disparity between injury and attendance to the RPCs. Determinants of improper wound treatment and delay of rabies PEP were identified by a stepwise multivariate logistic regression analysis. PRINCIPAL FINDINGS: In total, 1,015 animal bite victims (564 women and 451 men) responded to the questionnaire, and the response rate was 93.98%. Overall, 81.2% of animal bite victims treated their wounds improperly after suspected rabies exposure, and 35.3% of animal bite victims delayed the initiation of PEP. Males (OR = 1.871, 95% CI: 1.318-2.656), residents without college education (OR = 1.698, 95% CI: 1.203-2.396), participants liking to play with animals (OR = 1.554, 95% CI: 1.089-2.216), and people who knew the fatality of rabies (OR = 1.577, 95% CI: 1.096-2.270), were more likely to treat wounds improperly after an animal bite. Patients aged 15-44 years...