The Skyline ecosystem: Informatics for quantitative mass spectrometry proteomics

作者：Lindsay K. Pino, Brian C. Searle, James G. Bollinger, Brook L. Nunn, Brendan MacLean, Michael J. MacCoss · 发表于：Mass Spectrometry Reviews · 年份：2017 · DOI：10.1002/mas.21540 · 被引用次数：915 · 研究领域：Advanced Proteomics Techniques and Applications、Mass Spectrometry Techniques and Applications、Metabolomics and Mass Spectrometry Studies

Skyline is a freely available, open-source Windows client application for accelerating targeted proteomics experimentation, with an emphasis on the proteomics and mass spectrometry community as users and as contributors. This review covers the informatics encompassed by the Skyline ecosystem, from computationally assisted targeted mass spectrometry method development, to raw acquisition file data processing, and quantitative analysis and results sharing.