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An enzyme-free DNA walker that moves on the surface of functionalized magnetic microparticles and its biosensing analysis

作者:Ningxing Li, Jiao Zheng, Chunrong Li, Xinxin Wang, Xinghu Ji, Zhike He · 发表于:Chemical Communications · 年份:2017 · DOI:10.1039/c7cc04547f · 被引用次数:47 · 研究领域:Advanced biosensing and bioanalysis techniques、Nanocluster Synthesis and Applications、Biosensors and Analytical Detection

An enzyme-free stochastic DNA walker propelled by a single catalytic or double catalytic DNA assembly has been constructed. The application of the proposed DNA walking biosensor was successfully expanded to the detection of DNA and the enzymatic activity of T4 polynucleotide kinase.