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Binding Differences of Two Homochiral [Ru(bpy) 2 dppz] 2+ Complexes with poly(U)·poly(A)*poly(U) Triplex RNA

作者:Mengna Peng, Zhiyuan Zhu, Li-Feng Tan · 发表于:Inorganic Chemistry · 年份:2017 · DOI:10.1021/acs.inorgchem.7b00670 · 被引用次数:27 · 研究领域:Metal complexes synthesis and properties、RNA and protein synthesis mechanisms、DNA and Nucleic Acid Chemistry

The first investigation of chiral ruthenium(II) complexes Δ- and Λ-[Ru(bpy) 2 dppz] 2+ and triplex RNA poly(U)·poly(A)*poly(U) was carried out, which showed that Δ enantiomer displayed significant ability in stabilizing model triplex RNA.