Cancer drug delivery in the nano era: An overview and perspectives

作者：Zhen Li, Shirui Tan, Shuan Li, Qiang Shen, Kunhua Wang · 发表于：Oncology Reports · 年份：2017 · DOI：10.3892/or.2017.5718 · 被引用次数：405 · 研究领域：Nanoparticle-Based Drug Delivery、RNA Interference and Gene Delivery、Nanoplatforms for cancer theranostics

Nanomaterials are increasingly used as drug carriers for cancer therapy. Nanomaterials also appeal to researchers in the areas of cancer diagnosis and biomarker discovery. Several antitumor nanodrugs are currently being tested in preclinical and clinical trials and show promise in therapeutic and other settings. We review the development of nanomaterial drug carriers, including liposomes, polymer nanoparticles, dendritic polymers, and nanomicelles, for the diagnosis and treatment of various cancers. The prospects of nanomaterials as drug carriers for future clinical applications are also discussed.