The Hitchhiker’s Guide to Flow Chemistry

作者：Matthew B. Plutschack, Bartholomäus Pieber, Kerry Gilmore, Peter H. Seeberger · 发表于：Chemical Reviews · 年份：2017 · DOI：10.1021/acs.chemrev.7b00183 · 被引用次数：1973 · 研究领域：Innovative Microfluidic and Catalytic Techniques Innovation、Microfluidic and Capillary Electrophoresis Applications、Ionic liquids properties and applications

Flow chemistry involves the use of channels or tubing to conduct a reaction in a continuous stream rather than in a flask. Flow equipment provides chemists with unique control over reaction parameters enhancing reactivity or in some cases enabling new reactions. This relatively young technology has received a remarkable amount of attention in the past decade with many reports on what can be done in flow. Until recently, however, the question, "Should we do this in flow?" has merely been an afterthought. This review introduces readers to the basic principles and fundamentals of flow chemistry and critically discusses recent flow chemistry accounts.