The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity

作者：Jacquelyn A. Gorman, Christian Hundhausen, John S. Errett, Amy E.L. Stone, Eric J. Allenspach, Yan Ge, Tanvi Arkatkar, Courtnee A. Clough, Xuezhi Dai, Socheath Khim, Kathleen Pestal, Denny Liggitt, Karen M. Cerosaletti, Daniel B. Stetson, Richard G. James, Mohamed Oukka, PATRICK J. CONCANNON, Michael Gale, Jane Hoyt Buckner, David J. Rawlings · 发表于：Nature Immunology · 年份：2017 · DOI：10.1038/ni.3766 · 被引用次数：143 · 研究领域：interferon and immune responses、Immune Cell Function and Interaction、Cytokine Signaling Pathways and Interactions