Metal-free chloroamidation of indoles with sulfonamides and NaClO

作者：Xiaodong Liu, Kun Tong, Ai Hua Zhang, Ren Xiang Tan, Shouyun Yu · 发表于：Organic Chemistry Frontiers · 年份：2017 · DOI：10.1039/c7qo00199a · 被引用次数：23 · 研究领域：Catalytic C–H Functionalization Methods、Synthesis and Catalytic Reactions、Sulfur-Based Synthesis Techniques

An efficient and rapid protocol for chloroamidation of indoles with sulfonamides and aqueous NaClO has been developed. The reaction completes in less than half an hour at room temperature without any transition metals.