Green and Practical Oxidative Deoximation of Oximes to Ketones or Aldehydes with Hydrogen Peroxide/Air by Organoselenium Catalysis

作者：Xiaobi Jing, Dandan Yuan, Lei Yu · 发表于：Advanced Synthesis & Catalysis · 年份：2017 · DOI：10.1002/adsc.201601353 · 被引用次数：89 · 研究领域：Organoselenium and organotellurium chemistry、Sulfur-Based Synthesis Techniques、Organometallic Compounds Synthesis and Characterization

Abstract Organoselenium‐catalyzed oxidative deoximations afforded ketones and aldehydes under mild conditions. The reactions employ hydrogen peroxide and air as clean oxidants and lead to a waste‐free and metal‐free deprotection protocol for carbonyl protection strategies as well as the green synthesis of ketones and aldehydes. The mechanisms of this interesting organoselenium‐catalyzed reaction have been investigated by control experiments as well as the selenium 77 nuclear magnetic resonance ( 77 Se NMR) tests. This novel reaction largely expands the application scope of organoselenium catalysis. magnified image