The value of MRI in evaluating the efficacy and complications with the treatment of intra-arterial chemotherapy for retinoblastoma

作者：Shuxian Chen, Xunda Ji, Ming Liu, Zhengrong Xia, Hui Zheng, Qiufeng Yin, He Wang, Yuhua Li · 发表于：Oncotarget · 年份：2017 · DOI：10.18632/oncotarget.16423 · 被引用次数：18 · 研究领域：Ocular Oncology and Treatments、Brain Metastases and Treatment、Glioma Diagnosis and Treatment

// Shuxian Chen 1, * , Xunda Ji 2, * , Ming Liu 1 , Zhengrong Xia 1 , Hui Zheng 1 , Qiufeng Yin 1 , He Wang 3 , Yuhua Li 1 1 Department of Radiology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China 2 Department of Ophthalmology, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, China 3 Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai 200433, China * These authors have contributed equally to this work Correspondence to: Yuhua Li, email: liyuhua10@sina.com He Wang, email: hewang@fudan.edu.cn Keywords: retinoblastoma, intra-arterial chemotherapy, MRI, ADC value, children Received: December 23, 2016      Accepted: March 14, 2017      Published: March 21, 2017 ABSTRACT Retinoblastoma is the most common intraocular malignant tumor of childhood. Intra-arterial chemotherapy (IAC) is a recently popularized technique used for the treatment of retinoblastoma, to decrease mortality, increase preservation of the eye, and prevent blindness. Along with the extensive use of IAC, it is important to apply noninvasive examination methods to assess the activity of the tumor and the risk factors for disease dissemination without histopathological confirmation. There are few studies that have assessed the value of magnetic resonance imaging (MRI) in evaluating the efficacy and complications of IAC for re...