Validation of the chinese version of the EORTC QLQ-CR29 in patients with colorectal cancer

作者：Jinbo Lin, Lei Zhang, Dongwen Wu, Zhouhuan Xi, Xue-Jun Wang, Yunshou Lin, Wakana Fujiwara, Jingru Tian, Min Wang, Peng Peng, Ai Ye Guo, Zhen Yang, Le Luo, Ling-Ya Jiang, Qiaqia Li, Xueying Zhang, Yunfeng Zhang, Houwei Xu, Bing Yang, Xunlin Li, Yixiong Lei · 发表于：World Journal of Gastroenterology · 年份：2017 · DOI：10.3748/wjg.v23.i10.1891 · 被引用次数：32 · 研究领域：Stoma care and complications、Cancer survivorship and care、Colorectal Cancer Surgical Treatments

AIM: To assess the validity and reliability of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Colorectal Cancer 29 (EORTC QLQ-CR29) in Chinese patients with colorectal cancer (CRC). METHODS: From March 2014 to January 2015, 356 patients with CRC from four different hospitals in China were enrolled in the study, and all patients self-administered the EORTC QLQ-CR29 and the quality of life core questionnaire (EORTC QLQ-C30). Evaluation of the scores was based on the Karnofsky Performance Scale (KPS). The reliability and validity of the questionnaires were assessed by Cronbach's α coefficient, the Spearman correlation test and Wilcoxon rank sum test. RESULTS: > 0.4) and discriminant validity. Significant differences were obtained for each item in the different KPS subgroups (KPS ≤ 80; KPS > 80). Body image and most single-item dimensions showed statistically significant differences in patients with a stoma compared with the rest of the patients. CONCLUSION: The EORTC QLQ-CR29 exhibits high validity and reliability in Chinese patients with CRC, and can therefore be recommended as a valuable tool for the assessment of quality of life in these patients.