Deblur Rapidly Resolves Single-Nucleotide Community Sequence Patterns

作者：Amnon Amir, Daniel McDonald, José A. Navas-Molina, Evguenia Kopylova, James T. Morton, Zhenjiang Zech Xu, Eric P. Kightley, Luke Thompson, Embriette R. Hyde, Antonio González, Rob Knight · 发表于：mSystems · 年份：2017 · DOI：10.1128/msystems.00191-16 · 被引用次数：2009 · 研究领域：Genomics and Phylogenetic Studies、Gut microbiota and health、Microbial Community Ecology and Physiology

Deblur provides a rapid and sensitive means to assess ecological patterns driven by differentiation of closely related taxa. This algorithm provides a solution to the problem of identifying real ecological differences between taxa whose amplicons differ by a single base pair, is applicable in an automated fashion to large-scale sequencing data sets, and can integrate sequencing runs collected over time.