The Role of Healthy Lifestyle in the Implementation of Regressing Suboptimal Health Status among College Students in China: A Nested Case-Control Study

作者：Jieyu Chen, Hongjie Xiang, Pingping Jiang, Lin Yu, Yuan Jing, Fei Li, Shengwei Wu, Xiu‐Qiong Fu, Yanyan Liu, Hiu Yee Kwan, Ren Luo, Xiaoshan Zhao, Xiaomin Sun · 发表于：International Journal of Environmental Research and Public Health · 年份：2017 · DOI：10.3390/ijerph14030240 · 被引用次数：66 · 研究领域：Cardiovascular Health and Risk Factors、Health, Environment, Cognitive Aging、Health Promotion and Cardiovascular Prevention

BACKGROUND: Suboptimal health status (SHS) is the intermediate health state between health and disease, it is medically undiagnosed and is also termed functional somatic syndrome. Although its clinical manifestations are complicated and various, SHS has not reached the disease status. Unhealthy lifestyle is associated with many chronic diseases and mortality. In accordance with the impact of lifestyle on health, it is intriguing to determine the association between unhealthy lifestyle and SHS risk. METHODS: We conducted a nested case-control study among healthy Chinese college students from March 2012 to September 2013, which was nested in a prospective cohort of 5676 students. We performed 1:1 incidence density sampling with matched controls for birth year, sex, grade, specialty and individual character. SHS was evaluated using the medical examination report and Sub-health Measurement Scale V1.0 (SHMS V1.0). Exposure was defined as an unhealthy lifestyle per the frequency of six behavioral dimensions from the Health-promoting Lifestyle Profile (HPLP-II). RESULTS: We matched 543 cases of SHS (42.66%) in a cohort of 1273 students during the 1.5 years mean follow-up time with controls. A significant difference (t = 9.79, p < 0.001) and a reduction in HPLP-II total score was present at 1.5 years follow-up (135.93 ± 17.65) compared to baseline (144.48 ± 18.66). A level-response effect was recorded with an increase of the total HPLP-II (every dimension was correlated with a decrea...