Chromosome Painting in <b><i>Callicebus nigrifrons</i></b> Provides Insights into the Genome Evolution of Titi Monkeys and the Ancestral Callicebinae Karyotype

作者：Naiara Pereira Araújo, Alice Alves do Espírito Santo, Valéria do Socorro Pereira, Roscoe Stanyon, Marta Svartman · 发表于：Cytogenetic and Genome Research · 年份：2017 · DOI：10.1159/000458748 · 被引用次数：1 · 研究领域：Chromosomal and Genetic Variations、Genomic variations and chromosomal abnormalities、Genomics and Chromatin Dynamics

We studied the chromosomes of <i>Callicebus nigrifrons</i> with conventional and molecular cytogenetic methods<i>.</i> Our chromosome painting analysis in <i>C. nigrifrons</i> together with previous reports allowed us to hypothesize an ancestral Callicebinae karyotype with 2n = 48. The associations of human chromosomes (HSA) 2/22, 7/15, 10/11, and the inverted HSA2/16 would link <i>Callicebus, Cheracebus</i>, and <i>Plecturocebus</i> and would thus be present in the ancestral Callicebinae karyotype. Four fusions (HSA1b/1c, 3c/8b, 13/20, and 14/15/3/21) and 1 fission (HSA2/22) are synapomorphies of <i>Callicebus</i>. The associations HSA3/15 and HSA3/9 are chromosome features linking <i>Callicebus </i>and <i>Cheracebus</i>, whereas the association HSA13/17 would represent a link between <i>Callicebus </i>and the <i>moloch </i>group (<i>Plecturocebus</i>)<i>.</i> Only 6 of the 33 recognized titi monkey species have now been painted with human chromosome-specific probes. Further analyses are needed to clarify the phylogenomic relationships in this species-rich group.