Therapeutic mechanism of Yīn-Chén-Hāo decoction in hepatic diseases

作者：Jianyuan Li, Hongyan Cao, Lin Sun, Runfei Sun, Chao‐Liang Wu, Yanqin Bian, Shu Dong, Ping Liu, Mingyu Sun · 发表于：World Journal of Gastroenterology · 年份：2017 · DOI：10.3748/wjg.v23.i7.1125 · 被引用次数：70 · 研究领域：Saffron Plant Research Studies、Liver Disease Diagnosis and Treatment、Drug-Induced Hepatotoxicity and Protection

) that is used for the treatment of damp-heat jaundice. In modern clinics, YCHD is mostly used for hepatic diseases. This review summarizes the biological activities of YCHD and its medical applications. The main active compounds of YCHD are chlorogenic acid, rhein, geniposide, emodin, and scoparone. The pharmacological actions of YCHD include inhibition of hepatic steatosis, apoptosis, necrosis, anti-inflammation, and immune regulation. YCHD could be developed as a new therapeutic strategy for the treatment of hepatic diseases.