Trends and Patterns of Disparities in Cancer Mortality Among US Counties, 1980-2014

作者：Ali H. Mokdad, Laura Dwyer‐Lindgren, Christina Fitzmaurice, Rebecca W. Stubbs, Amelia Bertozzi-Villa, Chloe Morozoff, Raghid N. Charara, Christine A. Allen, Mohsen Naghavi, Christopher J L Murray · 发表于：JAMA · 年份：2017 · DOI：10.1001/jama.2016.20324 · 被引用次数：409 · 研究领域：Global Cancer Incidence and Screening、Head and Neck Cancer Studies、Multiple and Secondary Primary Cancers

Introduction: Cancer is a leading cause of morbidity and mortality in the United States and results in a high economic burden. Objective: To estimate age-standardized mortality rates by US county from 29 cancers. Design and Setting: Deidentified death records from the National Center for Health Statistics (NCHS) and population counts from the Census Bureau, the NCHS, and the Human Mortality Database from 1980 to 2014 were used. Validated small area estimation models were used to estimate county-level mortality rates from 29 cancers: lip and oral cavity; nasopharynx; other pharynx; esophageal; stomach; colon and rectum; liver; gallbladder and biliary; pancreatic; larynx; tracheal, bronchus, and lung; malignant skin melanoma; nonmelanoma skin cancer; breast; cervical; uterine; ovarian; prostate; testicular; kidney; bladder; brain and nervous system; thyroid; mesothelioma; Hodgkin lymphoma; non-Hodgkin lymphoma; multiple myeloma; leukemia; and all other cancers combined. Exposure: County of residence. Main Outcomes and Measures: Age-standardized cancer mortality rates by county, year, sex, and cancer type. Results: A total of 19 511 910 cancer deaths were recorded in the United States between 1980 and 2014, including 5 656 423 due to tracheal, bronchus, and lung cancer; 2 484 476 due to colon and rectum cancer; 1 573 593 due to breast cancer; 1 077 030 due to prostate cancer; 1 157 878 due to pancreatic cancer; 209 314 due to uterine cancer; 421 628 due to kidney cancer; 487 518...