Impact of postoperative glycemic control and nutritional status on clinical outcomes after total pancreatectomy

作者：Haojun Shi, Chen Jin, Deliang Fu · 发表于：World Journal of Gastroenterology · 年份：2017 · DOI：10.3748/wjg.v23.i2.265 · 被引用次数：38 · 研究领域：Pancreatic and Hepatic Oncology Research、Bariatric Surgery and Outcomes、Hyperglycemia and glycemic control in critically ill and hospitalized patients

AIM: To evaluate the impact of glycemic control and nutritional status after total pancreatectomy (TP) on complications, tumor recurrence and overall survival. METHODS: Retrospective records of 52 patients with pancreatic tumors who underwent TP were collected from 2007 to 2015. A series of clinical parameters collected before and after surgery, and during the follow-up were evaluated. The associations of glycemic control and nutritional status with complications, tumor recurrence and long-term survival were determined. Risk factors for postoperative glycemic control and nutritional status were identified. RESULTS: = 0.025) tended to have poor glycemic control and lower body mass index levels after TP, respectively. CONCLUSION: At least 3 mo are required after TP to adapt to diabetes and recover nutritional status. Glycemic control appears to have more influence over nutritional status on long-term outcomes after TP. Improvement in glycemic control and nutritional status after TP is important to prevent early complications and tumor recurrence, and improve survival.