Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

作者：Anna Rita Cantelmo, Lena-Christin Conradi, Aleksandra Brajic, Jermaine Goveia, Joanna Maria Kalucka, Andreas Pircher, Pallavi Chaturvedi, Johanna Hol Fosse, Bernard Thienpont, Laure-Anne Marie Nicole Teuwen, Sandra Schoors, Bram Boeckx, Joris Vriens, Anna Kuchnio, Koen Veys, Bert Cruys, Lise Finotto, Lucas Treps, Tor Espen Stav-Noraas, Francesco Bifari, Peter Conrad Stapor, Ilaria Decimo, Kim Rosalie Kampen, Katrien De Bock, Guttorm Haraldsen, Luc Schoonjans, Ton J. Rabelink, Guy Eelen, Bart Ghesquière, Jalees Rehman, Diether Lambrechts, Asrar B. Malik, Mieke A. Dewerchin, Peter Carmeliet · 发表于：Cancer Cell · 年份：2016 · DOI：10.1016/j.ccell.2016.10.006 · 被引用次数：683 · 研究领域：Cancer, Hypoxia, and Metabolism、Renal cell carcinoma treatment、Angiogenesis and VEGF in Cancer