Rosacea treatment update: recommendations from the global ROS acea CO nsensus ( ROSCO ) panel

作者：Martin Schaller, Luiz Maurício Costa Almeida, Anthony Bewley, B. Cribier, Ncoza C. Dlova, G. Kautz, Mark J. Mannis, Hazel H. Oon, Murlidhar Rajagopalan, Martin Steinhoff, Diane Thiboutot, Patricia Troielli, Guy Webster, Yan Wu, Esther J van Zuuren, Jerry Tan · 发表于：British Journal of Dermatology · 年份：2016 · DOI：10.1111/bjd.15173 · 被引用次数：156 · 研究领域：Acne and Rosacea Treatments and Effects、Dermatologic Treatments and Research、Skin Protection and Aging

BACKGROUND: Rosacea is currently treated according to subtypes. As this does not adequately address the spectrum of clinical presentation (phenotypes), it has implications for patient management. The ROSacea COnsensus panel was established to address this issue. OBJECTIVES: To incorporate current best treatment evidence with clinical experience from an international expert panel and establish consensus to improve outcomes for patients with rosacea. METHODS: Seventeen dermatologists and three ophthalmologists reached consensus on critical aspects of rosacea treatment and management using a modified Delphi approach. The panel voted on statements using the responses 'strongly disagree', 'disagree', 'agree' or 'strongly agree'. Consensus was defined as ≥ 75% 'agree' or 'strongly agree'. All voting was electronic and blinded. RESULTS: The panel agreed on phenotype-based treatments for signs and symptoms presenting in individuals with rosacea. First-line treatments were identified for individual major features of transient and persistent erythema, inflammatory papules/pustules, telangiectasia and phyma, underpinned by general skincare measures. Multiple features in an individual patient can be simultaneously treated with multiple agents. If treatment is inadequate given appropriate duration, another first-line option or the addition of another first-line agent should be considered. Maintenance treatment depends on treatment modality and patient preferences. Ophthalmological referra...