Neural circuits for pain: Recent advances and current views

作者：Cédric Peirs, Rebecca P. Seal · 发表于：Science · 年份：2016 · DOI：10.1126/science.aaf8933 · 被引用次数：488 · 研究领域：Pain Mechanisms and Treatments、Neuroscience and Neuropharmacology Research、Ion channel regulation and function

The mammalian nervous system encodes many different forms of pain, from those that arise as a result of short-term low-grade interactions with noxious thermal, chemical, or mechanical sources to more serious forms of pain induced by trauma and disease. In this Review, we highlight recent advances in our understanding of the neural circuits that encode these types of pain. Promising therapeutic strategies based on recent advances are also highlighted.