New organ allocation policy in liver transplantation in the United States

作者：David A. Goldberg, Richard Gilroy, Michael Charlton · 发表于：Clinical Liver Disease · 年份：2016 · DOI：10.1002/cld.580 · 被引用次数：14 · 研究领域：Liver Disease and Transplantation、Organ Transplantation Techniques and Outcomes、Liver Disease Diagnosis and Treatment

The content is the responsibility of the authors alone and does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products, or organizations imply endorsement by the U.S. Government. Potential conflict of interest: Nothing to report. The number of potential recipients who would benefit from being able to undergo liver transplantation is much greater than the supply of donated organs. Eight people die every day waiting for a liver transplant in the United States. The current organ allocation system, which prioritizes patients primarily according to Model for End‐Stage Liver Disease (MELD) score, is intended to direct organs to the sickest patients first. Wide geographic variations in availability of donor organs, the burden of liver disease, and population served, each of which has a multifactorial basis, have resulted in similarly wide variations in MELD score at transplant and likelihood of dying while waiting for a liver transplant. New allocation and distribution policies are under development that will reduce the geographic disparity in access to liver transplantation. Current Donor Liver Organ Allocation System The increasingly excellent outcomes and the increasing number of patients who might benefit from liver transplantation has produced a chronic shortage of donor organs for liver transplantation, with approximately one in six patients dying on the waitlist per year. Allocating or...