Updating the diagnosis, classification and assessment of rosacea: recommendations from the global ROS acea CO nsensus ( ROSCO ) panel

作者：Jerry Tan, Luiz Maurício Costa Almeida, Anthony Bewley, B. Cribier, Ncoza C. Dlova, Richard L. Gallo, G. Kautz, Mark J. Mannis, Hazel H. Oon, Murlidhar Rajagopalan, Martin Steinhoff, Diane Thiboutot, Patricia Troielli, Guy Webster, Yan Wu, Esther J van Zuuren, Martin Schaller · 发表于：British Journal of Dermatology · 年份：2016 · DOI：10.1111/bjd.15122 · 被引用次数：288 · 研究领域：Acne and Rosacea Treatments and Effects、Dermatologic Treatments and Research、Hidradenitis Suppurativa and Treatments

BACKGROUND: Rosacea is currently diagnosed by consensus-defined primary and secondary features and managed by subtype. However, individual features (phenotypes) can span multiple subtypes, which has implications for clinical practice and research. Adopting a phenotype-led approach may facilitate patient-centred management. OBJECTIVES: To advance clinical practice by obtaining international consensus to establish a phenotype-led rosacea diagnosis and classification scheme with global representation. METHODS: Seventeen dermatologists and three ophthalmologists used a modified Delphi approach to reach consensus on statements pertaining to critical aspects of rosacea diagnosis, classification and severity evaluation. All voting was electronic and blinded. RESULTS: Consensus was achieved for transitioning to a phenotype-based approach to rosacea diagnosis and classification. The following two features were independently considered diagnostic for rosacea: (i) persistent, centrofacial erythema associated with periodic intensification; and (ii) phymatous changes. Flushing, telangiectasia, inflammatory lesions and ocular manifestations were not considered to be individually diagnostic. The panel reached agreement on dimensions for phenotype severity measures and established the importance of assessing the patient burden of rosacea. CONCLUSIONS: The panel recommended an approach for diagnosis and classification of rosacea based on disease phenotype.