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Preparation and properties of reversible hydrogels based on triblock poly(amino acid)s with tunable pH‐responsivity across a broad range

作者:Dedai Lu, Yongyong Zhang, Yunfei Li, Chen Luo, Xiangya Wang, Xiaolin Guan, Hengchang Ma, Xiaolong Zhao, Qiangbing Wei, Ziqiang Lei · 发表于:Journal of Polymer Science Part A Polymer Chemistry · 年份:2016 · DOI:10.1002/pola.28375 · 被引用次数:18 · 研究领域:Hydrogels: synthesis, properties, applications、Polymer Surface Interaction Studies、Advanced Drug Delivery Systems

A series of reversible triblock poly(amino acid)s hydrogels with tunable pH-responsivity (pH 3.5–10.0) were synthesized by adjusting the ratio of the blocks. Attributing to the good biodegradability and low cytotoxicity of these triblock poly(amino acid)s, it is obvious that these poly(amino acid)s are potential novel materials in drug delivery and injectable hydrogels.