First Case of Laboratory-confirmed Zika Virus Infection Imported into China

作者：Yuanbin Zhong, Xiaoqing Liu, Yi-Chu Deng, Ping-Hua Xu, Gong-Rong Zhong, Wei Zhang · 发表于：Chinese Medical Journal · 年份：2016 · DOI：10.4103/0366-6999.187864 · 被引用次数：17 · 研究领域：Mosquito-borne diseases and control、Viral Infections and Vectors、Dengue and Mosquito Control Research

To the Editor: Zika virus (ZIKV) was first isolated from a rhesus monkey in the Zika forest in Uganda.[1] It is an emerging arbovirus of the Flaviviridae family, which includes Dengue, West Nile, yellow fever, and Japanese encephalitis viruses, and causes a mosquito-borne disease transmitted by the Aedes genus.[2] ZIKV was demonstrated explosion recently in American countries, especially in Brazil, Venezuela, and so on.[3] We reported a case of laboratory-confirmed ZIKV infection imported into China from Venezuela. The patient developed fever, rash, myalgia, headache, and conjunctivitis after returning to China from Venezuela on February 6, 2016. Serological investigations revealed positive ZIKV-specific real-time reverse transcription-polymerase chain reaction (RT-PCR). A previously healthy male Chinese traveler aged 34 years visited the doctor at the Second-class Hospital, Ganzhou, Jiangxi Province, China, on February 6, 2016, after returning from Venezuela for a business trip. During the patient's 9-day round trip (in lately January), he developed a joint fever (self-reported), dizziness, and chills on January 28, 2016. After 4 days (February 2, 2016), all these symptoms mentioned above aggravated slightly. However, this patient did not adopt any treatment and then went to Paris for another business trip. On the day he arrived in Paris (February 3, 2016), a slightly pruritic erythematous rash (not highlight the skin) appeared on his neck that later spread to his chest, arm...