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Photodynamic Therapy As a Promising Method Used in the Treatment of Oral Diseases

作者:Ewa Joanna Prażmo, Agnieszka Beata Mielczarek, Mirosław Kwaśny, M Łapiński · 发表于:Advances in Clinical and Experimental Medicine · 年份:2016 · DOI:10.17219/acem/32488 · 被引用次数:109 · 研究领域:Photodynamic Therapy Research Studies、Nanoplatforms for cancer theranostics、Dental Research and COVID-19

Photodynamic therapy (PDT) consists of three elements: photosensitizer, light and oxygen. The photosensitizer has the property of selective accumulation in abnormal or infected tissues without causing any damage to the healthy cells. This innovative therapeutic method has already been successfully adapted in many fields of medicine, e.g. dermatology, gynecology, urology and cancer therapy. Dentistry is also beginning to incorporate photodisinfection for treatment of the oral cavity. The antibacterial and fungicidal properties of the photosensitizer have been used to achieve better results in root canal treatment, periodontal therapy and the eradication of candidiasis in prosthodontics. The aim of this article is to discuss the effectiveness of photodynamic methods in the diagnosis and therapy of selected oral diseases. Scientific data and published papers regarding the antibacterial properties of PDT will be subjected to analysis. Photodynamic therapy will be discussed as an alternative treatment protocol in oncology, endodontics, periodontology and other fields of dentistry.