Common pitfalls in statistical analysis: Intention-to-treat versus per-protocol analysis

作者：Priya Ranganathan, Conjeevaram S. Pramesh, Rakesh Aggarwal · 发表于：Perspectives in Clinical Research · 年份：2016 · DOI：10.4103/2229-3485.184823 · 被引用次数：320 · 研究领域：Statistical Methods in Clinical Trials、Health Systems, Economic Evaluations, Quality of Life、Ethics in Clinical Research

During the conduct of clinical trials, it is not uncommon to have protocol violations or inability to assess outcomes. This article in our series on common pitfalls in statistical analysis explains the complexities of analyzing results from such trials and highlights the importance of "intention-to-treat" analysis.