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Design, synthesis and biological activity evaluation of novel conjugated sialic acid and pentacyclic triterpene derivatives as anti-influenza entry inhibitors

作者:Han Xu, Yongying Shi, Longlong Si, Zibo Fan, Han Wang, Renyang Xu, Pingxuan Jiao, Kun Meng, Zhen‐Yu Tian, Xiaoshu Zhou, Hongwei Jin, Xinyu Wu, Hong Chen, Yongmin Zhang, Lihe Zhang, Sulong Xiao, Demin Zhou · 发表于:MedChemComm · 年份:2016 · DOI:10.1039/c6md00292g · 被引用次数:24 · 研究领域:Natural product bioactivities and synthesis、Toxin Mechanisms and Immunotoxins、Pharmacological Effects of Natural Compounds

A total of 24 novel sialic acid–pentacyclic triterpene conjugates were synthesized and evaluated as anti-influenza virus entry inhibitors.