The genetic architecture of type 2 diabetes

作者：Christian Fuchsberger, Jason A. Flannick, Tanya M. Teslovich, Anubha Mahajan, Vineeta Agarwala, Kyle J. Gaulton, Clement Ma, Pierre Fontanillas, Loukas Moutsianas, Davis James McCarthy, Manuel A. Rivas, John R. B. Perry, Xueling Sim, Thomas W. Blackwell, Neil R. Robertson, Nigel William Rayner, Pablo Cingolani, Adam E. Locke, Juan Fernández Tajes, Heather M. Highland, Josée Dupuis, Peter S. Chines, Cecilia M. Lindgren, Christopher Hartl, Anne Jackson, Han Chen, Jeroen R. Huyghe, Martijn van de Bunt, Richard D. Pearson, Ashish Kumar, Martina Müller‐Nurasyid, Niels Grarup, Heather M. Stringham, Eric R. Gamazon, Jaehoon Lee, Yuhui Chen, Robert A. Scott, Jennifer E. Below, Peng Chen, Jinyan Huang, Min Jin Go, Michael L. Stitzel, Dorota Pasko, Stephen C.J. Parker, Tibor V. Varga, Todd Green, Nicola L. Beer, Aaron Day-Williams, Teresa Cruz Ferreira, Tasha E. Fingerlin, Momoko Horikoshi, Cheng Hu, Iksoo Huh, M. Kamran Ikram, Bong-Jo Kim, Yongkang Kim, Young Jin Kim, Min‐Seok Kwon, Juyoung Lee, Selyeong Lee, Keng‐Han Lin, Taylor J. Maxwell, Yoshihiko Nagai, Xu Wang, Ryan Welch, Joon Ho Yoon, Weihua Zhang, Nir Barzilai, Benjamin Franklin Voight, Bok‐Ghee Han, Christopher P. Jenkinson, Teemu Kuulasmaa, Johanna Kuusisto, Alisa Knodle Manning, Maggie C. Y. Ng, Nicholette D. Palmer, Beverley Balkau, Alena Stančáková, Hanna E. Abboud, Heiner Boeing, Vilmantas Giedraitis, Dorairaj Prabhakaran, Omri Gottesman, James Scott, Jason Carey, Phoenix Kwan, George Grant, Joshua D. Smith, Benjamin M. Neale, Shaun Purcell, Adam S. Butterworth, Joanna M. M. Howson, Heung Man Lee, Yingchang Lu, Soo‐Heon Kwak, Wei Zhao, John Danesh, Vincent K. L. Lam, Kyong Soo Park, Danish Saleheen, Wing Yee So, Claudia H.T. Tam, Uzma Afzal, David Aguilar, Rector Arya, Tin Aung, Edmund Chan, Carmen Navarro, Ching‐Yu Cheng, Domenico Palli, Adolfo Correa, Joanne E. Curran, Denis Rybin, Vidya S. Farook, Sharon P. Fowler, Barry I. Freedman, Michael E Griswold, Daniel Esten Hale, Pamela J. Hicks, Chiea Chuen Khor, Satish Kumar, Benjamin C. Lehne, Dorothée Thuillier, Wei Yen Lim, Jianjun Liu, Yvonne T. van der Schouw, Marie Chiew Shia Loh, Solomon K. Musani, Sobha Puppala, William R. Scott, Loïc Yengo, Sian-Tsung Tan, Herman A. Taylor, Farook Thameem, Gregory A Wilson, Tien Yin Wong, Pål R. Njølstad, Jonathan Cummings Levy, Massimo Mangino, Lori L. Bonnycastle, Thomas Schwarzmayr, João P. S. Fadista, Gabriela L. Surdulescu, Christian Herder, Christopher J. Groves, Thomas Wieland, Jette Bork‐Jensen, Ivan Brandslund, Cramer Christensen, Heikki A. Koistinen, Alex S. F. Doney, Leena Kinnunen, Tõnu Esko, Andrew J. Farmer, Liisa Hakaste, Dylan Hodgkiss, Jasmina Kravić, Valeriya Lyssenko, Mette Hollensted, Marit E. Jørgensen, Torben Jørgensen, Claes Ladenvall, Johanne Marie Justesen, Annemari Käräjämäki, Jennifer Kriebel, Wolfgang Rathmann, Lars Lannfelt, Torsten Lauritzen, Narisu Narisu, Allan R Linneberg, Olle Melander, Lili A. Milani, Matt J. Neville, Marju Orho‐Melander, Lu Qi, Qibin Qi, Michael Roden, Olov Rolandsson, Amy J. Swift, Anders H. Rosengren, Kathleen E. Stirrups, Andrew R. Wood, Evelin Mihailov, Christine Blancher, Mauricio O. Carneiro, Jared Maguire, Ryan E. Poplin, Khalid Shakir, Timothy R. Fennell, Mark A. DePristo, Martin Hrabě de Angelis, Panos Deloukas, Anette P. Gjesing, Goo Jia Jun, Peter M. Nilsson, Jacquelyn Murphy, Robert C. Onofrio, Barbara Thorand, Torben F. Hansen, Christa Meisinger, Frank B. Hu, Bo Isomaa, Fredrik Karpe, Liming Liang, Annette Peters, Cornelia Huth, Stephen O’Rahilly, Colin N. A. Palmer, Oluf Borbye Pedersen, Rainer Rauramaa, Jaakko Tuomilehto, Veikko V Salomaa, Richard M. Watanabe, Ann‐Christine Syvänen, Richard N. Bergman, Dwaipayan Bharadwaj, Erwin P. Böttinger, Yoon Shin Cho, Giriraj R. Chandak, Juliana C.N. Chan, Kee Seng Chia, Mark J. Daly, Shah B. Ebrahim, Claudia Langenberg, Paul Elliott, Kathleen A. Jablonski, Donna M. Lehman, Weiping Jia, Ronald C.W., Toni I. Pollin, Manjinder S. Sandhu, Nikhil Tandon, Philippe Froguel, Inês Barroso, Yik Ying Teo, Eleftheria Zeggini, Ruth J. F. Loos, Kerrin S. Small, Janina S. Ried, Ralph Anthony DeFronzo, Harald Grallert, Benjamin Gläser, Andres Metspalu, Nicholas J. Wareham, Mark F. Walker, Eric Banks, Christian Gieger, Erik Ingelsson, Hae Kyung Im, Thomas Illig, Paul W. Franks, Gemma Buck, Joseph Trakalo, David Buck, Inga Prokopenko, Reedik Mägi, Lars Lind, Yossi Farjoun, Katharine R. Owen, Anna L. Gloyn, Konstantin Strauch, Tiinamaija Tuomi, Jaspal Singh Kooner, Jong‐Young Lee, Taesung Park, Peter Donnelly, Andrew D. Morris, Andrew Tym Hattersley, Donald W. Bowden, Francis S. Collins, Gil Atzmon, John Campbell Chambers, Timothy D. Spector, Markku Laakso, Tim Matthias Strom, Graeme I. Bell, John Blangero, Ravindranath Duggirala, E Shyong Tai, Gilean McVean, Craig L. Hanis, James G. Wilson, Mark T. Seielstad, Timothy Mark Frayling, James B. Meigs, Nancy Jean Cox, Robert Sladek, Eric S. Lander, Stacey L. Gabriel, Noël P. Burtt, Karen L. Mohlke, Thomas Meitinger, Leif Groop, Gonçalo R. Abecasis, José C. Florez, Laura J. Scott, Andrew Paul Morris, Hyun Min Kang, Michael Boehnke, David Altshuler, Mark I. McCarthy · 发表于：Nature · 年份：2016 · DOI：10.1038/nature18642 · 被引用次数：1129 · 研究领域：Genetic Associations and Epidemiology、Bioinformatics and Genomic Networks、Epigenetics and DNA Methylation