Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2

作者：Satoshi Inoue, Wanda Y. Li, Alan Tseng, Isabel Beerman, Andrew Elia, Sean C. Bendall, François Lemonnier, Ken J. Kron, David W. Cescon, Zhenyue Hao, Evan Lind, Naoya Takayama, Aline Cristiane Planello, Shu Yi Shen, Alan H. Shih, Dana M. Larsen, Qinxi Li, Bryan E. Snow, Andrew Wakeham, Jillian Haight, Chiara Gorrini, C. Bassi, Kelsie L. Thu, Kiichi Murakami, Alisha R. Elford, Takeshi Ueda, Kimberly Straley, Katharine Yen, Gerry Melino, Luisa Cimmino, Iannis Aifantis, Ross L. Levine, Daniel D. De Carvalho, Mathieu Lupien, Derrick J. Rossi, Garry P. Nolan, Rob A. Cairns, Tak W. Mak · 发表于：Cancer Cell · 年份：2016 · DOI：10.1016/j.ccell.2016.05.018 · 被引用次数：200 · 研究领域：Acute Myeloid Leukemia Research、Epigenetics and DNA Methylation、Cancer Genomics and Diagnostics