[Morphologic changes in acute central serous chorioretinopathy evaluated by spectral domain optical coherence tomography].

作者：Hai Yu, Guo-ying Xia, Minghong Gao, Jing Yu, Yan-ying Zhang · 发表于：PubMed · 年份：2011 · 被引用次数：4 · 研究领域：Ophthalmology、Medicine、Pathology

OBJECTIVE: To describe the pathologic changes of macular in acute central serous chorioretinopathy (CSC) using spectral domain optical coherence tomography (SD-OCT). METHODS: It was a retrospective case series study. This study included 29 eyes of 29 patients with CSC. The fundus examination was conducted followed by SD-OCT to observe foveal microstructure changes. We evaluated the correlation between the thickness of the outer nuclear layer (ONL), the length of photoreceptors and best-corrected visual acuity (BCVA). RESULTS: Serous retinal detachment was found in all 29 eyes with SD-OCT. There was no obvious morphology change in ONL, the thickness of ONL was (96.94 ± 23.72) µm and did not different from that in normal control eyes (104.15 ± 11.90) µm. The thickness of photoreceptors was uniform in 11 eyes (31.9%), uniform but with defects in 6 eyes (20.7%), uneven in 4 eyes (13.8%), protruding of outer segments (OS) was observed in 6 eyes (20.7%) and flaking OS in 2 eyes (6.9%). The length from external limiting membrane to the longest outer segment in CSC eyes was 84 (52 to 148) µm and was not statistically different from that in normal eyes (69 to 82)µm. Morphology changes of retinal pigment epithelium (RPE) were found in 25 eyes, including pigment epithelial detachment of RPE (PED) in 21 eyes (72.4%), small bulge of RPE in 10 eyes (34.5%), granular deposition epi-RPE in 6 eyes (20.7%), defects of RPE in 3 eyes (10.3%). Fluorescein angiography (FA) was performed in 5 eyes ...