Prolactin cell carcinoma of the pituitary.

作者：Vira Kasantikul, Darunee Boonjunwetwat, Pongsepeera Suwangool · 发表于：PubMed · 年份：1993 · 被引用次数：21 · 研究领域：Pituitary Gland Disorders and Treatments、Glioma Diagnosis and Treatment、Neuroblastoma Research and Treatments

Two patients with malignant prolactinoma are reported. The diagnosis of malignancy depends on the demonstration of invasion of brainstem and subarachnoid space and on the presence of marked cellular pleomorphism and mitotic activity. Review of the literature revealed that such malignant tumors were more common in men than in women. The most frequency intracranial sites of metastases were frontal and occipital lobes, and cerebellum. The possibility of radiation-induced carcinomatous transformation is discussed.