Biological and Immunological Characterization of Purified Follicle‐Stimulating Hormone Preparations From Monkey Pituitaries

作者：Shafiq A. Khan, Berit Fröysa, E. Diczfalusy · 发表于：Journal of Medical Primatology · 年份：1984 · DOI：10.1111/j.1600-0684.1984.tb00147.x · 被引用次数：16 · 研究领域：Hypothalamic control of reproductive hormones、Stress Responses and Cortisol、Growth Hormone and Insulin-like Growth Factors

The suitability of a purified rhesus (rhFSH) and cynomolgus (cynFSH) follicle-stimulating hormone (FSH) preparation to replace the expired LER 1909-2 reference standard in the immunoassay of monkey FSH was assessed using an in vitro bioassay and two heterologous radioimmunoassay (RIA) procedures in combination with fractionation by high-resolution isoelectrofocusing. The results presented indicate that rhFSH is unsuitable for the replacement of LER 1909-2 as a standard, though cynFSH might be suitable after the removal of its LH contamination.