Regional assignment of catalase (CAT) gene to band 11p13. Association with the aniridia-Wilms' tumor-Gonadoblastoma (WAGR) complex.

作者：Claudine Junien, CATHERINE TURLEAU, de Grouchy J, Rizna A. Said, Rethoré Mo L, Romano Tenconi, Dufier Jl · 发表于：PubMed · 年份：1980 · 被引用次数：77 · 研究领域：Renal and related cancers、Epigenetics and DNA Methylation、Animal Genetics and Reproduction

A gene dosage effect for catalase (CAT) was investigated in three individuals : one with 11p13 deletion, aniridia, ambiguous genitalla, and gonadoblastoma ; one trisomic for 11p with the exception of 11p13; and one trisomic for 11p13. Results were compatible with the assignment of CAT to 11p13 and its linkage with the aniridia-gonadoblastoma or Wilms' tumor complex (WAGR).