Whole-body PET with (fluorine-18)-2-deoxyglucose for detecting recurrent ovarian carcinoma. Initial report.

作者：Chiou Chung Yuan, Ren Shyan Liu, Peng Hui Wang, Heung Tat Ng, Shin Hwa Yeh · 发表于：PubMed · 年份：1999 · 被引用次数：37 · 研究领域：Ovarian cancer diagnosis and treatment、Endometrial and Cervical Cancer Treatments、Medical Imaging Techniques and Applications

OBJECTIVE: To investigate positron emission tomography (PET) with (fluorine-18)-2-deoxyglucose (FDG) for detecting recurrent ovarian carcinoma. STUDY DESIGN: Wholebody FDG-PET scanning was performed on five patients before surgical exploration. All five patients were suspected of having recurrence based upon clinical findings and underwent surgery after scanning. RESULTS: In all five patients, PET images demonstrated increased FDG uptake in a distribution that correlated with surgical-pathologic findings (100%); computer tomography can detect 60% of such patients with malignant disease. Two cases with unexplained elevated serum CA-125 had lesions localized by PET. CONCLUSION: Recurrence of ovarian carcinoma was clearly imaged with FDG-PET and was confirmed by surgical pathology. FDG-PET might be a fairly effective tool for detecting recurrent ovarian carcinoma.