An acute gastroenteritis outbreak caused by GII.17 norovirus in Jiangsu Province, China

作者：Chao Shi, Weihong Feng, Ping Shi, Jing Ai, Hongxia Guan, Dan Sha, Qian Geng, Jun Mei, Shan-Hui Chen, Yong Xiao, Yan-Hua Qian · 发表于：International Journal of Infectious Diseases · 年份：2016 · DOI：10.1016/j.ijid.2016.05.004 · 被引用次数：16 · 研究领域：Viral gastroenteritis research and epidemiology、Viral Infections and Immunology Research

Noroviruses are a common cause of acute gastroenteritis around the world; however, reports of outbreaks caused by GII.17 norovirus are rare. An outbreak caused by GII.17 norovirus in a senior high school in Wuxi, Jiangsu Province, China is reported here. An epidemiological investigation, pathogen detection, and case-control study were performed. Epidemiological data combined with the epidemic curve indicated that this outbreak was a point source type initially, followed by secondary transmission. The first case was identified as most likely the source of the outbreak. Risk analysis showed exposure to patients and sharing a communal water cooler to be associated with the spread of infection. Sequence analysis of GII-positive samples confirmed that the norovirus GII.17 variant was the etiological agent of this outbreak.