Ni(acac)2-Catalyzed Addition Reactions of Aryl- and Alkylboronic Acids to Tryptanthrins

作者：Hong‐Ping Xiao, Jun Jiang, Wei-Long Chen, Chong‐Xing Liu · 发表于：Synlett · 年份：2016 · DOI：10.1055/s-0035-1562229 · 被引用次数：9 · 研究领域：Quinazolinone synthesis and applications、Synthesis and Biological Evaluation、Phenothiazines and Benzothiazines Synthesis and Activities

A Ni(acac) 2 -catalyzed 1,2-addition reaction of tryptanthrins with aryl- or alkylboronic acids gave the corresponding indoloquinazolinone-type quaternary alcohols in 30–90% yield. Importantly, this reaction showed a good tolerance of functional groups and a remarkably broad substrate scope that included substrates bearing halogen atoms.