[Study on anti-HPV activity of Asarum heterotropoides].

作者：Yuanhui Deng, Yi Feng, Sun Jing, Dan Zhou, Yang Liu, Jiaying Lai · 发表于：PubMed · 年份：2004 · 被引用次数：7 · 研究领域：Chemistry、Virology、Biochemistry、Biology

OBJECTIVE: To screen anti-HPV effective fraction from Asarum heterotropoides. METHODS: Asarum heterotropoides was extracted with systematic solvents (petroleum benzine, ether, ethyl acetate, n-butanol, ethanol and distilled water) accordingly. The Polymerase Chain Reaction (FQ-PCR) was applied in the vitro pharmacodynamics for the extracts from Asarum heterotropoides. The amplification of HPV-DNA in the lesions of the isolated Condyloma acuminatum. RESULTS: After the water extracts of Asarum heterotropoides was used for HPV-DNA, the PCR amplification showed negative, with the minimum effective concentration 0.4 g/ml. But the other solvents extracts from Asarum heterotropoides appeared positive. CONCLUSION: The water extracts from Asarum heterotropoides are effective on anti-Human papillomavirus.