Ultrasound Synthesis of 2,3,4,6-Tetra-O-acetyl-1-chloro-1-bromo-β-D-pyranose

作者：Zhou Sheng · 发表于：Huadong Li-Gong Daxue xuebao · 年份：2003 · 研究领域：Synthesis and Characterization of Heterocyclic Compounds

1,2,3,4,6PentaOacetylβDpyranosyl bromide and 2,3,4,6tetraOacetyl1chloro1bromoβDpyranose were synthesized by ultrasound technique. Result showed that with the different power and different frequency of ultrasonic wave, the changes of power and frequency of ultrasonic wave have a deep impact on the reaction rate, yield and selectivity. At the same power, the reaction rate and yield increased and good selectivity attained with the increase of frequency. With the same frequency, the reaction yield increased and good selectivity resulted with the increasing of power. ESR technique proved that the reaction of these pyranosyl bromides is a radical reaction.