Investigation of Traditional Chinese Medical Constitution of Type 2 Diabetes Mellitus Patients and Its Relationship with Insulin Resistance and Insulin Secretion

作者：WU Xiao-qiu · 发表于：Guangzhou Zhongyiyao Daxue xuebao · 年份：2013 · 被引用次数：2 · 研究领域：Traditional Chinese Medicine Studies

Objective To investigate the the characteristics of traditional Chinese medical constitution of patients with type 2 diabetes mellitus(T2DM),and to explore the relationship of Chinese medical constitution types with the related risk factors.Methods A questionnaire survey was conducted in 147 patients with type 2 diabetes mellitus,and the characteristics of their constitution as well as the relationship of constitution types with risk factors of insulin resistance index(IRI) and insulin sensitivity index(ISI)was analyzed.Results Yin-deficiency constitution(24.49%) was the main constitution types of T2DM,and then came blood-stasis constitution(14.29%),Qi-deficiency constitution(12.93%),phlegm-damp constitution(12.24%),normal constitution(8.84%),yang-deficiency constitution(6.80%),damp-heat constitution(10.20%),Qi-depression constitution(6.12%),and special constitution(4.08%).Yin-deficiency constitution showed significant difference with the other types of constitution(P 0.01).Phlegm-damp constitution had the highest IRI and the lowest ISI(P 0.01).Yin-deficiency constitution had the lowest function levels of islet beta cell(P0.05 or P0.01).All of the constitution types were correlated with diabetic risk factors such as smoking,alcohol consumption,body mass index(BMI),waist to hip ratio(WHR),fasting plasma glucose(FPG),fasting C-peptide,fasting insulin(FINS),HbA1c,lipids,and inflammatory factors to various degrees(P0.05 or P0.01).Conclusion The constitution types of T2DM patients...