Toxic Effects of Norfloxacin on the Growth and the Activity of Antioxidase of Chlorella pyrenoidosa

作者：Yu-Feng Yang · 年份：2007 · 被引用次数：8 · 研究领域：Water Quality Monitoring and Analysis、Aquatic Ecosystems and Phytoplankton Dynamics、Marine and coastal ecosystems

Chlorella pyrenoidosa was chosen as the test material to study the toxic effects of Norfloxacin on algae by acute toxicity test and a battery of biochemical parameters such as EROD, GST and CAT enzymes activities of algae in this research. The results showed that the 96h EC50 was 30.78mg·L-1 in NFLX exposure, NFLX was low-toxic to Chlorella pyrenoidosa. The activities of Glutathione S-transferase(GST) and catalase(CAT) had sensitive responses to the exposure of NFLX. CAT was induced at initial stages and inhibited gradually with the rising of NFLX concentration; while GST was induced significantly when exposed to over 30mg·L-1 NFLX and increased continuously with the rising of NFLX concentration. The activities of Glutathione(GSH) and 7-ethoxyresorufin-O-deethylase(EROD) had slight variances among different treatments groups. CAT and GST may act as the potential biomarkers of NFLX exposure at low concentration to Chlorella pyrenoidosa.