Altered Activity of the Sodium-Potassium Pump in Arteries of Rats with Steroid Hypertension

作者：Motilal B. Pamnani, David L. Clough, Francis J. Haddy · 发表于：Clinical Science · 年份：1978 · DOI：10.1042/cs055041s · 被引用次数：58 · 研究领域：Nitric Oxide and Endothelin Effects、Hormonal Regulation and Hypertension、Ion Transport and Channel Regulation

1. Ouabain-sensitive uptake of 86Rb, a measure of the Na+-K+ pump activity, was studied in tail arteries of rats made hypertensive with deoxycorticosterone and saline. 2. Decreased activity of the ouabain-sensitive Na+-K+ pump supports the hypothesis that the activity of Na+-K+ pump is suppressed in volume expanded hypertension.