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Dimeric Erythrina Alkaloids from the Flower of Erythrina variegata

作者:Bing‐Jie Zhang, Mei‐Fen Bao, Chun‐Xia Zeng, Xiu-Hong Zhong, Ling Ni, Ying Zeng, Xiang‐Hai Cai · 发表于:Organic Letters · 年份:2014 · DOI:10.1021/ol503190z · 被引用次数:59 · 研究领域:Bioactive natural compounds、Synthesis of Organic Compounds、Synthesis and biological activity

Unprecedented dimeric Erythrina alkaloids, spirocyclic (6/5/6/6) erythrivarine A (1) and spiro-fused (6/5/7/6) rings erythrivarine B (2), were isolated from the cultivated plant, E. variegata. The structures were determined on the basis of 1D and 2D NMR, FTIR, UV, and mass spectroscopic data and X-ray crystal diffraction. The biogenetic relationship of 1 and 2 is proposed.