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Colony Formation by Normal and Leukemic Human Marrow Cells in Culture: Effect of Conditioned Medium From Human Leukocytes

作者:Norman N. Iscove, John S. Senn, James E. Till, E. A. McCulloch · 发表于:Blood · 年份:1971 · DOI:10.1182/blood.v37.1.1.1 · 被引用次数:487 · 研究领域:Mesenchymal stem cell research、RNA Interference and Gene Delivery、Cancer Cells and Metastasis

Abstract "Conditioned medium" obtained from cultures of human peripheral leukocytes promoted the growth of human marrow cells in cell culture. This material also permitted the growth of small colonies from the marrow of patients with acute myelogenous leukemia in relapse; in its absence, only occasional colonies were observed.