Castor Oil-Based Biodegradable Polyesters

作者：Konda Reddy Kunduru, Arijit Basu, Moran Haim Zada, Abraham J. Domb · 发表于：Biomacromolecules · 年份：2015 · DOI：10.1021/acs.biomac.5b00923 · 被引用次数：158 · 研究领域：Polymer composites and self-healing、Electrospun Nanofibers in Biomedical Applications、biodegradable polymer synthesis and properties

This Review compiles the synthesis, physical properties, and biomedical applications for the polyesters based on castor oil and ricinoleic acid. Castor oil has been known for its medicinal value since ancient times. It contains ∼90% ricinoleic acid, which enables direct chemical transformation into polyesters without interference of other fatty acids. The presence of ricinoleic acid (hydroxyl containing fatty acid) enables synthesis of various polyester/anhydrides. In addition, castor oil contains a cis-double bond that can be hydrogenated, oxidized, halogenated, and polymerized. Castor oil is obtained pure in large quantities from natural sources; it is safe and biocompatible.