Prostaglandins and related factors: XIX. Thin-layer chromatography of prostaglandins

作者：Krister Gréen, Bengt O. Samuelsson · 发表于：Journal of Lipid Research · 年份：1964 · DOI：10.1016/s0022-2275(20)40270-6 · 被引用次数：481 · 研究领域：Inflammatory mediators and NSAID effects、Analytical Methods in Pharmaceuticals、Analytical Chemistry and Chromatography

Methods are described for separation of all known prostaglandins and some derivatives as free acids and methyl esters by thin-layer chromatography both on analytical and preparative scales. The use of silica gel containing silver nitrate was required for separations of compounds differing in the degree of unsaturation whereas ordinary silica gel was suitable for group separations of prostaglandin E, prostaglandin Fα, and prostaglandin FΒ, compounds.