Myocardial arterial spin labeling

作者：Frank Kober, Terrence Jao, Thomas Troalen, Krishna S. Nayak · 发表于：Journal of Cardiovascular Magnetic Resonance · 年份：2016 · DOI：10.1186/s12968-016-0235-4 · 被引用次数：53 · 研究领域：Advanced MRI Techniques and Applications、Cardiac Imaging and Diagnostics、Electron Spin Resonance Studies

Arterial spin labeling (ASL) is a cardiovascular magnetic resonance (CMR) technique for mapping regional myocardial blood flow. It does not require any contrast agents, is compatible with stress testing, and can be performed repeatedly or even continuously. ASL-CMR has been performed with great success in small-animals, but sensitivity to date has been poor in large animals and humans and remains an active area of research. This review paper summarizes the development of ASL-CMR techniques, current state-of-the-art imaging methods, the latest findings from pre-clinical and clinical studies, and future directions. We also explain how successful developments in brain ASL and small-animal ASL-CMR have helped to inform developments in large animal and human ASL-CMR.